About PRP Therapy for Hair Rejuvination
What is PRP for Hair Loss?
Platelet Rich Plasma Therapy To best understand hair loss and therefore how Platelet Rich Plasma for Hair Loss, it is important to review the causes of hair loss further.
Hair Loss known as Male Pattern Baldness or Androgenetic Alopecia, impacts both men and women and is evident when a person experiences hair loss that is limited to the Frontal, Midscalp and Crown regions of the head – (See Figure )
To understand hair loss, we suggest to patients to think of your hair like any normal plant. For a plant to grow, it requires; A Seed, and, the right growing conditions for it to flourish – the seed requires the right quantity and quality of nutrients.
In the image below, you will see the growing cycle of a plant, from seed to healthy and full bodied plant –(See Figure 2.1).
In this next sequence below, consider what will happen if the seed no longer receives the nutrients it needs to keep the plant that it grows thick and full. If nutrients to the seed drops, the healthy & full plant will wither or thin – (See Figure 2.2). If nothing is done to improve the quantity and/or quality of the nutrients the seed receives, the degeneration of the plant will continue until the seed “dies”. Once that seed is dead, it will not produce a blade of grass.
In the next sequence, the blade of grass gets a boost of nutrients, it will then start to build up the healthiness of the blade of grass and somewhat help it improve its lushness – (See Figure 2.3).
In summary, think of your hair like a plant:
- 1. For a plant to grow, you need a seed.
- 2. That seed needs to get the right quality and quantity of nutrients from the environment around it.
- 3. If the supply of nutrients reduces, the seed will not receive the right quality or quantity of nutrients is requires to continue growing a thick and full plant.
- 4. If the nutrient levels continue to fall, the seed will eventually “die” and once that happens that seed will no longer produce a plant.
- 5. Improving the quality or quantity of nutrients a seed receives will assist in slowing down the rate of hair loss/thinning associated with genetic hair loss.
Now lets compare this to a hair and relate it to hair loss associated with Androgenetic Alopecia. This genetic condition, creates the outcome where there is a lack of blood supply reaching to your hair follicle due to the presence of a hormone DHT. This image shows how DHT acts in a way to starve the hair follicle of the nutrients it needs to produce a thick, full and healthy hair shaft – (See Figure 3.1).
Thick of hair loss in a new way, due to a reduction in the supply of your own bodies ferlister (your blood), Platelet Rich Plasma seeks to directly supply your thinning hair follicles with the nutrients it is failing to receive, and this reduction in nutrient supply can offer preventative and rejuvenation results.
Platelet Rich Plasma Therapy most commonly known as PRP acts as a “fertilizer” for the follicle. This Medical Procedure involves extracting a patients blood, and the platlets are then isolated by using a centrafuge. The platelets are then injected directly into the follicle – (See Figure 3.2).
PRP for Hair is an exciting relatively new hair loss treatment that is promoting and yielding excellent preventative outcomes whilst promoting rejuvenation results. What is Platelet Rich Plasma PRP?
- .PRP stands for Platelet-Rich Plasma
- An autologous (coming from the same person) preparation of platelets in concentrated plasma
- The volume of the plasma fraction of the autologous blood with platelets that are above the baseline normal platelet level
- Safe and promotes natural healing
- It is considered a great alternative to surgery
- A new effective treatment option for people who have severe forms of hair loss problems
- Promote effective wound healing
- Has skin-rejuvenating effects that are useful in the fields of dermatology and aesthetic surgery
- Stimulate human dermal fibroblasts and improve wrinkling
- Can increase the yield of transplanted follicular units for those with androgenetic alopecia
- Has full complement of clotting and growth factors
The other names for PRP Platelet Rich Plasma are:
- 1. Platelet Enriched Plasma
- 2. Platelet Rich Concentrate
- 3. Autologous Platelet Gel
- 4. Platelet Releasate
- 5. Vampire Cure
How long has it been used world wide?
- Considered to have clinical benefits in hair restoration since the early 1990s
- First used by Ferrari et al. following an open heart surgery, to avoid excessive transfusion of homologous blood products in 1987
The Methods involved in PRP Platelet Rich Plasma
- Initially extract a minimum 10mL of the patient’s own blood.
- Using a centrifuge, separate the platelets from other blood components, this process will see platelet concentrations increased to more than a million of platelets/1L
- 1. Extraction of 10-60 mL of venous blood from the antecubital vein using gauge 18 or 19 butterfly needle to avoid irritation and trauma to the platelets.
- 2. Placement of the extracted blood into an approved device and proceed with centrifugation for 15 minutes at 3,200 rpm.
- 3. Separation of the blood into Platelet Poor Plasma, RBC and Platelet-Rich Plasma.
- 4. Extraction of Platelet Poor Plasma through a special port and discarding it from the device.
- 5. Shaking of the device for 30 seconds to re-suspend the platelets in the PRP found in the vacuumed space of the device.
- 6. Withdrawal of the PRP for administration/graft procedure.
Other industries using PRP Platelet Rich Plasma
- 1. Orthopedics
- 2. Sports Medicine
- 3. Dentistry
- 4. Ear Nose & Throat Surgeons
- 5. Neurosurgery
- 6. Ophthalmology
- 7. Urology
- 8. Diabetic Wound Healing
- 9. Cosmetic
- 10. Cardiothoracic
- 11. Maxillofacial surgery
- 12. Periodontal and Oral surgery
- 13. Trauma SurgeryPlastic surgery
- 14. Spinal surgery
- 15. Heart bypass surgery
- 16. Burns rehabilitation
Risks of PRP Platelet Rich Plasma
- 1. Infection if correct sterilisation not completed
- 2. Bleeding
- 3. Nerve damage
- 4. Localised Pain
- 5. Allergic reaction or local toxicity to anesthetics such as Bupivocaine HCL or Lidocaine
- 6. Neurovascular injury
- 7. Scar tissue formation
- 8. Calcification at the injection site
Benefits of PRP Platelet Rich Plasma
- 1. No immunogenic reactions or disease transmission
- 2.No studies telling us that PRP can lead to hyperplasia, cancer, or tumor growth
- 3. Leads to therapeutic effect on male and female pattern hair loss (androgenetic alopecia) without major side-effects
- 4. Increase in survival of hair follicle cells through the antiapoptotic effects on dermal papilla cells
- 5. Hair growth may be stimulated by prolonging the anagen phase of the hair cycle
- 6. Effective therapy for treatment of inflammation
- 7. Good for post-operative blood loss treatment
- 8. Can help treat infection
- 9. Can alleviate pain and improve function
- 10. Promote wound healing
- 11. Can treat patients with osteoarthritis
- 12. Enhance the healing process of tissues
Platelet Rich Plasma: Contraindications
- According to the Guidelines for the Use of Platelet Rich Plasma, the following are the identified contraindications.
- Absolute Contraindications
- Platelet dysfunction syndrome
- Critical thrombocytopenia
- Hemodynamic instability
- Local infection at the site of the procedure
- Patient unwilling to accept risks
- active breastfeeding
- Relative Contraindications
- Consistent use of NSAIDs within 48 hours of procedure
- Corticosteroid injection at treatment site within 1 month
- Systemic use of corticosteroids within 2 weeks
- Tobacco use
- Recent fever or illness
- Cancer- especially hematopoetic or of bone
- HGB < 10 g/dl
- Platelet count < 105/ul
Preparation before a PRP Procedure
- Physician or appropriate medical professional determines that PRP Platelet Rich Plasma is suitable for the patient
- Blood test
- Adequate hydration at least 48 hours before the procedure
- Reduced fat intake in the diet
- Avoid alcohol and caffeine
- Omegas, green teas and all supplements that can increase bruising must be stopped